LABOCOR, S.L.

Coat colour and variation horse

Each horse has a basic coat colour, which can be black, bay/brown or chestnut. Estos colores básicos de la capa son controlados por los genes Extension y Agouti. The Extension gene controls the production of black and red pigment while the distribution of black pigment is controlled by the agouti gene.

The rest of the colour genes act as modifiers (dilution or depigmentation) on the basic coat colour of the horse. There are at least five genes that dilute the coat colour of the horse: Cream, Champagne, Dun, Pearl, and Silver. The pattern genes modify the colour of the horse by deleting colour (depigmentation). These genes include Overo, Sabino, Tobiano, Grey, dominant white, white spotting, Appaloosa spotting and Pattern-1. For Appaloosa spotting VHLGenetics doesn’t offer a test yet.

Within the above described coat colour genes, three genes explain the major differences; the Agouti, Extension and Cream dilution genes. In the table below the possible combinations of the genes are indicated.

Coat Colour

Agouti

Extension

Cream Dilution

Black

a/a

E/E of E/e

N/N

Brown or Bay

A/A of A/a

E/E of E/e

N/N

Chestnut

A/A, A/a of a/a

e/e

N/N

Smoky black

a/a

E/E of E/e

N/Cr

Buckskin

A/A of A/a

E/E of E/e

N/Cr

Palomino

A/A, A/a of a/a

e/e

N/Cr

Smoky cream

a/a

E/E of E/e

Cr/Cr

Perlino

A/A of A/a

E/E of E/e

Cr/Cr

Cremello

A/A, A/a of a/a

e/e

Cr/Cr

 

BASIC COLOUR:

P904 Coat Colour Chestnut

Each horse has a basic colour, which can be black, bay/brown or chestnut. Estos colores básicos de la capa son controlados por los genes Extension y Agouti. El gen de extensión (E-locus) controla la producción de pigmento negro y rojo. La prueba de Color Castaño (P904) analiza el estado genético del gen Extensión. El gen de la extensión tiene dos variantes (alelos). El alelo dominante E produce pigmento negro y el alelo recesivo e produce pigmento rojo. Todos los caballos, independientemente del color de su pelaje, tienen la genética del pigmento negro o rojo. Los caballos rojos (por ejemplo, castaño, acedera, palomino y cremello) tienen dos copias del alelo recesivo e, también llamado eo homocigoto. Los caballos pigmentados en negro (por ejemplo, negro, marrón, marrón, negro ahumado, piel de ante, crema ahumada y perlino) tienen al menos una copia del alelo E. Pueden ser homocigotos EE o heterocigotos Ee.

The Coat Colour Chestnut test encloses the following results, in this scheme the results of the Coat Colour Chestnut test are shown in combination with the possible results for the Coat Colour Agouti test:

Result Chestnut

Result Agouti

Coat Colour

Descripción

e/e

A/A, A/a or a/a

Chestnut, Sorrel

Only the recessive allele e was detected, the horse is homozygous for red pigment (ee). The basic colour is chestnut or sorrel unless modified by other colour modifying genes. It can only pass on allele e to its offspring.

E/e

a/a

Black

The horse is heterozygous for red pigment (Ee). The basic colour is black unless modified by other colour modifying genes. It can pass on either allele E or e to its offspring.

E/e

A/A or A/a

Bay, Brown

The horse is heterozygous for red pigment (Ee). The basic colour is bay or brown unless modified by other colour modifying genes. It can pass on either allele E or e to its offspring.

E/E

a/a

Black

Only the dominant allele E was detected, the horse is homozygous for black pigment (EE). The basic colour is black unless modified by other colour modifying genes. It can only pass on allele E to its offspring and therefore cannot produce red foals.

E/E

A/A or A/a

 

Bay, Brown

Only the dominant allele E was detected, the horse is homozygous for black pigment (EE). The basic colour is bay or brown unless modified by other colour modifying genes. It can only pass on allele E to its offspring and therefore cannot produce red foals.

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P907 Coat Colour Agouti

Each horse has a basic colour, which can be black, bay/brown or chestnut. Estos colores básicos de la capa son controlados por los genes Extension y Agouti. The Agouti gene (A-locus) controls the distribution of black pigment. The pigment can be uniformly distributed or distributed to the “points” of the body (mane, tail, lower legs and inside the ears). The Agouti gene has no effect on horses that are homozygous ee for the Extension gene as black pigment has to be present for agouti to have an effect. The Coat Colour Agouti test (P907) tests for the genetic status of the Agouti gene. The Agouti gene has two variants (alleles). The dominant allele A restricts black pigment to the points of the horse (for example in bays and buckskins) and the recessive allele a uniformly distributes black pigment over the entire body. Only when the horse has two copies of the recessive allele a (homozygous aa), the black pigment is evenly distributed. The black pigment is distributed into the points if at least one copy of the allele A is present. All horses, regardless of their coat colour do have the genetics for the distribution of black pigment, but it’s not always physically visible.

The Coat Colour Agouti test encloses the following results, in this scheme the results of the Coat Colour Agouti test are shown in combination with the possible results for the Coat Colour Chestnut test:

Result Agouti

Result Chestnut

Coat Colour

Descripción

a/a

E/E or E/e

Black

Only the recessive allele a was detected. The black pigment is distributed uniformly. If the horse is not e/e for the Extension gene, the basic colour is black unless modified by other colour modifying genes. It can only pass on allele a to its offspring.

a/a

e/e

Chestnut, Sorrel

Only the recessive allele a was detected. The black pigment is distributed uniformly. Because the horse is e/e for the Extension gene, the basic colour is chestnut or sorrel unless modified by other colour modifying genes. It can only pass on allele a to its offspring.

A/a

E/E or E/e

Bay, Brown

The horse is tested heterozygous for Agouti. The black pigment is distributed into the points. If the horse is not e/e for the Extension gene, the basic colour is bay or brown unless modified by other colour modifying genes. It can pass on either allele A or a to its offspring.

A/a

e/e

Chestnut, Sorrel

The horse is tested heterozygous for Agouti. The black pigment is distributed into the points. Because the horse is e/e for the Extension gene, the basic colour is chestnut or sorrel unless modified by other colour modifying genes. It can pass on either allele A or a to its offspring.

A/A

E/E or E/e

Bay, Brown

Only the dominant allele A was detected. The black pigment is distributed into the points. If the horse is not e/e for the Extension gene, the basic colour is bay or brown unless modified by other colour modifying genes. It can only pass on allele A to its offspring and therefore cannot produce black foals.

A/A

e/e

Chestnut, Sorrel

Only the dominant allele A was detected. The black pigment is distributed into the points. Because the horse is e/e for the Extension gene, the basic colour is chestnut or sorrel unless modified by other colour modifying genes. It can only pass on allele A to its offspring and therefore cannot produce black foals.

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DILUTIONS:

P713 Coat Colour Cream dilution

The cream dilution gene has an effect on both red and black pigment and dilutes the basic coat colour to lighter coat shades. In several breeds this is considered a desirable trait. The Cream dilution gene is responsible for the palomino, buckskin, smoky black, cremello, perlino and smoky cream coat colours. A horse can also carry mutations for other modifying genes which can further affect its coat colour. The Coat Colour Cream dilution test (P713) tests for the genetic status of the MATP gene. The MATP gene has two variants (alleles). The allele Cr is semi-dominant. One copy of the Cr allele dilutes the coat colour with a single dose, resulting in palomino, buckskin or smoky black. Two copies of the Cr allele dilute the coat colour with a double dose into cremello, perlino or smoky cream. The effect on black pigment might be very subtle. Horses with two copies of the Cr allele are also called “double-dilutes” or “blue-eyed cream” and they share a number of characteristics. The eyes are pale blue, paler than the unpigmented blue eyes associated with white color or white markings, and the skin is rosy-pink. El alelo N es recesivo y no tiene efecto en el color básico.

The Coat Colour Cream dilution test encloses the following results, in this scheme the results of the Coat Colour Cream dilution test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Cream dilution

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

Non-dilute. The basic colour is chestnut or sorrel unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Non-dilute. The basic colour is bay or brown unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Non-dilute. The basic colour is black unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/Cr

e/e + A/A, A/a or a/a

 

Palomino

 

Heterozygous dilute, one copy of the Cr allele. The basic coat colour chestnut/sorrel is diluted to palomino. These colours can be further modified by other colour modifying genes. It can pass on either allele N or Cr to its offspring.

N/Cr

E/E or E/e + A/A or A/a

Buckskin

Heterozygous dilute, one copy of the Cr allele. The basic coat colour bay/brown is diluted to buckskin. These colours can be further modified by other colour modifying genes. It can pass on either allele N or Cr to its offspring.

N/Cr

E/E or E/e + a/a

Smoky Black

Heterozygous dilute, one copy of the Cr allele. The basic coat colour black is diluted to Smoky Black. These colours can be further modified by other colour modifying genes. It can pass on either allele N or Cr to its offspring.

Cr/Cr

e/e + A/A, A/a or a/a

 

Cremello

 

Double dilute, two copies of the Cr allele. The basic coat colour chestnut/sorrel is diluted to Cremello. These colours can be further modified by other colour modifying genes. It can only pass on allele Cr to its offspring.

Cr/Cr

E/E or E/e + A/A or A/a

Perlino

Double dilute, two copies of the Cr allele. The basic coat colour bay/brown is diluted to Perlino. These colours can be further modified by other colour modifying genes. It can only pass on allele Cr to its offspring.

Cr/Cr

E/E or E/e + a/a

Smoky Cream

Double dilute, two copies of the Cr allele. The basic coat colour black is diluted to Smoky Cream. These colours can be further modified by other colour modifying genes. It can only pass on allele Cr to its offspring.

VOLVER ARRIBA

P853 Coat Colour Champagne dilution

The Champagne dilution gene lightens the coat colour of the horse by diluting the pigment. The skin of Champagne-diluted horses is pinkish/lavender toned and becomes speckled with age; the speckling is particularly noticeable around the eye, muzzle, under the tail, udder and sheath. The eye colour is blue-green at birth and darkens to amber as the horse ages. Champagne has the following effects on the basic coat colours of horses:

Chestnut/Sorrel -> Gold champagne:   a gold body color and often a flaxen mane and tail. Gold champagne horses are visually similar to palomino horses.

Bay/Brown -> Amber champagne:       a tan body color with brown points

                                                             (sometimes referred to as amber Buckskin)

Black -> Classic champagne:               a darker tan body with brown points

A horse can also carry mutations for other modifying genes which can further affect its coat colour. The Coat Colour Champagne dilution test (P853) tests for the genetic status of the SLC36A1 gene. Este gen tiene dos variantes (alelos). The dominant allele Ch results in the dilution and the recessive allele N does not have an effect on the basic colour.

The Coat Colour Champagne dilution test encloses the following results, in this scheme the results of the Coat Colour Champagne dilution test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Champagne dilution

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

Non-dilute. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Non-dilute. The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Non-dilute. The basic colour black is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/Ch

e/e + A/A, A/a or a/a

 

Gold Champagne

 

One copy of the dominant Ch allele. The basic colour chestnut/sorrel is diluted to gold champagne unless modified by other colour modifying genes. It can pass on either allele N or Ch to its offspring.

N/Ch

E/E or E/e + A/A or A/a

Amber Champagne

One copy of the dominant Ch allele. The basic colour bay/brown is diluted to amber champagne unless modified by other colour modifying genes. It can pass on either allele N or Ch to its offspring.

N/Ch

E/E or E/e + a/a

Classic Champagne

One copy of the dominant Ch allele. The basic colour black is diluted to classic champagne unless modified by other colour modifying genes. It can pass on either allele N or Ch to its offspring.

Ch/Ch

e/e + A/A, A/a or a/a

 

Gold Champagne

 

Two copies of the dominant Ch allele. The basic colour chestnut/sorrel is diluted to Gold Champagne unless modified by other colour modifying genes. It can only pass on allele Ch to its offspring.

Ch/Ch

E/E or E/e + A/A or A/a

Amber Champagne

Two copies of the dominant Ch allele. The basic colour bay/brown is diluted to amber champagne unless modified by other colour modifying genes. It can only pass on allele Ch to its offspring.

Ch/Ch

E/E or E/e + a/a

Classic Champagne

Two copies of the dominant Ch allele. The basic colour black is diluted to classic champagne unless modified by other colour modifying genes. It can only pass on allele Ch to its offspring.

VOLVER ARRIBA

P660 Coat Colour Dun dilution

The Dun dilution gene lightens the coat colour of the horse by lightening the body colour, leaving the head, lower legs, mane and tail undiluted. Dun is also typically characterized by “primitive markings”, allmost all dun horses possess at least the dorsal stripe, but the presence of the other primitive markings varies. Other common markings may include horizontal striping on the legs, transverse striping across the shoulders, and lighter guard hairs along the edges of a dark mane and tail. Dun diluted coat colour with primitive markings is considered the “wild-type” colour and is found in wild equids such as przewalski horses. Dun dilutes both red and black pigment, and the resulting colors range from apricot, golden, dark gray, olive and many more subtle variations. A horse can also carry mutations for other modifying genes which can further affect its coat colour. The Coat Colour Dun dilution test (P660) tests for the genetic status of the TBX3 gene. This gene has three variants (alleles); allele D is dominant over the alleles nd1 and nd2; allele nd1 is dominant over nd2. The dominant allele D results in Dun dilution with primitive markings. Allele nd1 does not dilute the coat colour of the horse, primitive markings are present but the expression is variable. Allele nd2 does not have an effect on the basic colour.

The Coat Colour Dun dilution test encloses the following results, in this scheme the results of the Coat Colour Dun dilution test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Dun dilution

Result Chestnut + Agouti

Coat Colour

Descripción

nd2/nd2

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel. No primitive markings

Two copies of the nd2 allele. Coat colour is not diluted and primitive markings are absent. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele nd2 to its offspring.

nd2/nd2

E/E or E/e + A/A or A/a

Bay, Brown. No primitive markings

Two copies of the nd2 allele. Coat colour is not diluted and primitive markings are absent. The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele nd2 to its offspring.

nd2/nd2

E/E or E/e + a/a

Black. No primitive markings

Two copies of the nd2 allele. Coat colour is not diluted and primitive markings are absent. The basic colour black is not modified unless modified by other colour modifying genes. It can only pass on allele nd2 to its offspring.

nd1/nd2

e/e + A/A, A/a or a/a

 

 

Chestnut, Sorrel. Primitive markings may be present

One copy of the nd1 allele and one copy of the nd2 allele. The nd1 allele is dominant over the nd2 allele. Coat colour is not diluted. Primitive markings may be present. The colour can be further modified by other colour modifying genes. It can pass on either allele nd1 or nd2 to its offspring.

nd1/nd2

E/E or E/e + A/A or A/a

Bay, Brown. Primitive markings may be present

One copy of the nd1 allele and one copy of the nd2 allele. The nd1 allele is dominant over the nd2 allele. Coat colour is not diluted. Primitive markings may be present. The colour can be further modified by other colour modifying genes. It can pass on either allele nd1 or nd2 to its offspring.

nd1/nd2

E/E or E/e + a/a

Black. Primitive markings may be present

One copy of the nd1 allele and one copy of the nd2 allele. The nd1 allele is dominant over the nd2 allele. Coat colour is not diluted. Primitive markings may be present. The colour can be further modified by other colour modifying genes. It can pass on either allele nd1 or nd2 to its offspring.

nd1/nd1

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel. Primitive markings may be present

Two copies of the nd1 allele. Coat colour is not diluted. Primitive markings may be present. The colour can be further modified by other colour modifying genes. It can only pass on allele nd1 to its offspring.

nd1/nd1

E/E or E/e + A/A or A/a

Bay, Brown. Primitive markings may be present

 

Two copies of the nd1 allele. Coat colour is not diluted. Primitive markings may be present. The colour can be further modified by other colour modifying genes. It can only pass on allele nd1 to its offspring.

nd1/nd1

E/E or E/e + a/a

Black. Primitive markings may be present

 

Two copies of the nd1 allele. Coat colour is not diluted. Primitive markings may be present. The colour can be further modified by other colour modifying genes. It can only pass on allele nd1 to its offspring.

D/nd2

e/e + A/A, A/a or a/a

 

Red dun. With primitive markings

One copy of the dominant D allele and one copy of the nd2 allele. Coat colour is dun-diluted with primitive markings. The colour can be further modified by other colour modifying genes. It can pass on either allele D or nd2 to its offspring.

D/nd2

E/E or E/e + A/A or A/a

Bay dun. With primitive markings

One copy of the dominant D allele and one copy of the nd2 allele. Coat colour is dun-diluted with primitive markings. The colour can be further modified by other colour modifying genes. It can pass on either allele D or nd2 to its offspring.

D/nd2

E/E or E/e + a/a

Blue dun. With primitive markings

One copy of the dominant D allele and one copy of the nd2 allele. Coat colour is dun-diluted with primitive markings. The colour can be further modified by other colour modifying genes. It can pass on either allele D or nd2 to its offspring.

D/nd1

e/e + A/A, A/a or a/a

 

Red dun. With primitive markings

One copy of the dominant D allele and one copy of the nd1 allele. Coat colour is dun-diluted with primitive markings. The colour can be further modified by other colour modifying genes. It can pass on either allele D or nd1 to its offspring.

D/nd1

E/E or E/e + A/A or A/a

Bay dun. With primitive markings

One copy of the dominant D allele and one copy of the nd1 allele. Coat colour is dun-diluted with primitive markings. The colour can be further modified by other colour modifying genes. It can pass on either allele D or nd1 to its offspring.

D/nd1

E/E or E/e + a/a

Blue dun. With primitive markings

One copy of the dominant D allele and one copy of the nd1 allele. Coat colour is dun-diluted with primitive markings. The colour can be further modified by other colour modifying genes. It can pass on either allele D or nd1 to its offspring.

D/D

e/e + A/A, A/a or a/a

Red dun. With primitive markings

Two copies of the dominant D allele. Coat colour is dun-diluted with primitive markings. The colour can be further modified by other colour modifying genes. It can only pass on allele D to its offspring.

D/D

E/E or E/e + A/A or A/a

Bay, Classic, Zebra dun. With primitive markings

Two copies of the dominant D allele. Coat colour is dun-diluted with primitive markings. The colour can be further modified by other colour modifying genes. It can only pass on allele D to its offspring.

D/D

E/E or E/e + a/a

Blue, Mouse dun. With primitive markings

Two copies of the dominant D allele. Coat colour is dun-diluted with primitive markings. The colour can be further modified by other colour modifying genes. It can only pass on allele D to its offspring.

VOLVER ARRIBA

P783 Coat Colour Pearl dilution

The Pearl dilution gene lightens the coat colour of the horse by diluting the red pigment. A chestnut basic colour is diluted to a pale, uniform apricot colour of body, mane and tail. Skin coloration is also pale. Pearl dilution is also referred to as the 'Barlink Factor.' The Coat Colour Pearl dilution test (P783) tests for the genetic status of the SLC45A2 gene. Este gen tiene dos variantes (alelos). The allele Prl, causing the Pearl dilution is recessive. This means that only horses with two copies of the Prl allele have a lightened coat, mane and tail, in addition to bright eye colors. The dominant allele N does not have an effect on the basic coat colour.

Pearl dilution interacts with Cream dilution to produce pseudo-double dilute phenotypes including pale skin and blue/green eyes. Therefore if a horse has one copy of the Prl allele and Cream dilution (Cr allele) is also present, this results in a pseudo-double dilute, also called pseudo-cremellos or pseudo-smoky cream

A horse can also carry mutations for other modifying genes which can further affect its coat colour.

The Coat Colour Pearl dilution test encloses the following results, in this scheme the results of the Coat Colour Pearl dilution test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Pearl dilution

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

Chestnut, Sorrel

Non-dilute. The basic colour chestnut/sorrel is not diluted unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Non-dilute. The basic colour bay/brown is not diluted unless modified by other colour modifying genes. It can only pass on allele N to its offspring

N/N

E/E or E/e + a/a

Black

Non-dilute. The basic colour black is not diluted unless modified by other colour modifying genes. It can only pass on allele N to its offspring

N/Prl

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

One copy of the recessive Prl allele. The basic colour chestnut/sorrel is not diluted unless modified by other colour modifying genes. If cream dilution is also present, this results in a pseudo-double dilute. It can pass on either allele N or Prl to its offspring.

N/Prl

E/E or E/e + A/A or A/a

Bay, Brown

One copy of the recessive Prl allele. The basic colour bay/brown is not diluted unless modified by other colour modifying genes. If cream dilution is also present, this results in a pseudo-double dilute. It can pass on either allele N or Prl to its offspring.

N/Prl

E/E or E/e + a/a

Black

One copy of the recessive Prl allele. The basic colour black not diluted unless modified by other colour modifying genes. If cream dilution is also present, this results in a pseudo-double dilute. It can pass on either allele N or Prl to its offspring.

Prl/Prl

e/e + A/A, A/a or a/a

 

Pearl dilution

Two copies of the recessive Prl allele. The basic colour chestnut/sorrel is diluted to a pale, uniform apricot colour of body hair, mane and tail. This colour can be further modified by other colour modifying genes. It can only pass on allele Prl to its offspring.

Prl/Prl

E/E or E/e + A/A or A/a

Pearl dilution

Two copies of the recessive Prl allele. The basic colour bay/brown is diluted to lightened coat, mane and tail. This colour can be further modified by other colour modifying genes. It can only pass on allele Prl to its offspring.

Prl/Prl

E/E or E/e + a/a

Pearl dilution

Two copies of the recessive Prl allele. The basic colour black is diluted to lightened coat, mane and tail. This colour can be further modified by other colour modifying genes. It can only pass on allele Prl to its offspring.

VOLVER ARRIBA

P784 Coat Colour Silver dilution / MCOA

The Silver dilution gene dilutes the black pigment but has no effect on the red pigment. El efecto del gen de dilución Plata puede variar mucho. La crin y la cola se abrillantan a lino o gris plata y pueden oscurecer en algunos caballos conforme envejecen. Un caballo negro se diluirá al chocolate con un aclarado de la melena y la cola. Un caballo bahía con dilución Plata tendrá generalmente un aclarado en crines y cola, así como en la parte baja de las patas (lugares con pigmento negro). A horse can also carry mutations for other modifying genes which can further affect its coat colour.

The Coat Colour Silver dilution test (P784) tests for the genetic status of the PMEL17 gene. Este gen tiene dos variantes (alelos). El alelo dominante Z resulta en la dilución y el alelo recesivo N no tiene un efecto sobre el color básico.

The same mutation responsible for the coat color Silver is also associated with Multiple Congenital Ocular Anomalies (MCOA) Syndrome, a wide range of ocular defects that occur in the anterior and posterior parts of the eye. La gravedad del síndrome está relacionada con la dosis, por lo que los caballos con 1 copia del alelo Z tienen menos signos graves que aquellos con 2 copias del alelo Z.

The Coat Colour Silver dilution test encloses the following results, in this scheme the results of the Coat Colour Silver dilution test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Silver dilution

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

Non-dilute. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Non-dilute. The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Non-dilute. The basic colour black is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/Z

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

One copy of the dominant Z allele. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can pass on either allele N or Z to its offspring.

N/Z

E/E or E/e + A/A or A/a

Silver dilution on Bay or Brown

One copy of the dominant Z allele. The black pigment of bay/brown horses on lower legs is lightened and mane and tail are lightened to flaxen. The colour can be further modified by other colour modifying genes. It can pass on either allele N or Z to its offspring.

N/Z

E/E or E/e + a/a

Chocolate

One copy of the dominant Z allele. The basic colour black is diluted to chocolate with flaxen mane and tail. The colour can be further modified by other colour modifying genes. It can pass on either allele N or Z to its offspring.

Z/Z

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

Two copies of the dominant Z allele. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele Z to its offspring.

Z/Z

E/E or E/e + A/A or A/a

Silver dilution on Bay or Brown

Two copies of the dominant Z allele. The black pigment of bay/brown horses on lower legs is lightened and mane and tail are lightened to flaxen. The colour can be further modified by other colour modifying genes. It can only pass on allele Z to its offspring.

Z/Z

E/E or E/e + a/a

Chocolate

Two copies of the dominant Z allele. The basic colour black is diluted to chocolate with flaxen mane and tail. The colour can be further modified by other colour modifying genes. It can only pass on allele Z to its offspring.

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Patterns:

P591 Coat Colour Dominant White 1

White patterning in horses is known as Dominant White or White. Los patrones dominantes en blanco son variables, desde manchas mínimas tipo Sabino hasta caballos completamente blancos. El color de los ojos de los caballos blancos dominantes es marrón. Hay alrededor de 20 mutaciones diferentes identificadas que están asociadas con patrones blancos, todas las mutaciones se encuentran en el gen KIT. A excepción de W20, la mayoría de las mutaciones blancas dominantes conocidas surgieron recientemente y están restringidas a líneas específicas dentro de razas. La prueba Color de Capa Blanco Dominante 1 (P591) analiza la mutación conocida como W18 en el gen KIT. Esta prueba detecta dos variantes (alelos). El alelo W18 es dominante. Una o dos copias del alelo W18 dan como resultado caballos que muestran cierto grado de manchas blancas, pero el patrón específico no se puede predecir. El alelo N es recesivo y no tiene efecto en el color básico.

The Coat Colour Dominant White 1 test encloses the following results, in this scheme the results of the Coat Colour Dominant White 1 test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Dominant White 1

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

Not Dominant White. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Not Dominant White. The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Not Dominant White. The basic colour black is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/W18

e/e + A/A, A/a or a/a

 

Chestnut/sorrel with Dominant White pattern

Dominant White pattern. One copy of the W18 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or W18 to its offspring.

N/W18

E/E or E/e + A/A or A/a

Brown/bay with Dominant White pattern

Dominant White pattern. One copy of the W18 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or W18 to its offspring.

N/W18

E/E or E/e + a/a

Black with Dominant White pattern

Dominant White pattern. One copy of the W18 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or W18 to its offspring.

W18/W18

e/e + A/A, A/a or a/a

Chestnut/sorrel with Dominant White pattern

Dominant White pattern. Two copies of the W18 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele W18 to its offspring.

W18/W18

E/E or E/e + A/A or A/a

Brown/bay with Dominant White pattern

Dominant White pattern. Two copies of the W18 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele W18 to its offspring.

W18/W18

E/E or E/e + a/a

Black with Dominant White pattern

Dominant White pattern. Two copies of the W18 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele W18 to its offspring.

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P592 Coat Colour Dominant White 3

White patterning in horses is known as Dominant White or White. Los patrones dominantes en blanco son variables, desde manchas mínimas tipo Sabino hasta caballos completamente blancos. El color de los ojos de los caballos blancos dominantes es marrón. Hay alrededor de 20 mutaciones diferentes identificadas que están asociadas con patrones blancos, todas las mutaciones se encuentran en el gen KIT. A excepción de W20, la mayoría de las mutaciones blancas dominantes conocidas surgieron recientemente y están restringidas a líneas específicas dentro de razas. La prueba Color de Capa Blanco Dominante 3 (P592) analiza la mutación conocida como W20 en el gen KIT. Esta prueba detecta dos variantes (alelos). El alelo W20 es dominante. Una o dos copias del alelo W20 tienen un efecto sutil sobre la cantidad de blanco expresado. Parece aumentar la expresión del blanco en combinación con otros genes de patrón blanco. El alelo N es recesivo y no tiene efecto en el color básico.

The Coat Colour Dominant White 3 test encloses the following results, in this scheme the results of the Coat Colour Dominant White 3 test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Dominant White 3

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

Not Dominant White. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Not Dominant White. The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Not Dominant White. The basic colour black is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/W20

e/e + A/A, A/a or a/a

 

Chestnut/sorrel with Dominant White pattern

Dominant White pattern. One copy of the W20 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or W20 to its offspring.

N/W20

E/E or E/e + A/A or A/a

Brown/bay with Dominant White pattern

Dominant White pattern. One copy of the W20 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or W20 to its offspring.

N/W20

E/E or E/e + a/a

Black with Dominant White pattern

Dominant White pattern. One copy of the W20 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or W20 to its offspring.

W20/W20

e/e + A/A, A/a or a/a

Chestnut/sorrel with Dominant White pattern

Dominant White pattern. Two copies of the W20 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele W20 to its offspring.

W20/W20

E/E or E/e + A/A or A/a

Brown/bay with Dominant White pattern

Dominant White pattern. Two copies of the W20 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele W20 to its offspring.

W20/W20

E/E or E/e + a/a

Black with Dominant White pattern

Dominant White pattern. Two copies of the W20 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele W20 to its offspring.

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P593 Coat Colour Macchiato (Splashed White)

In 2008 a colt with a striking white-spotting coat colour was born out of two solid-coloured bay Franches-Montagnes parents. The coat colour looks like a combination of white-spotting and coat colour dilution and it was named ‘‘macchiato’’. A clinical examination revealed that the macchiato stallion was deaf and had a low progressive sperm motility.

The Coat Macchiato (Splashed White)  test (P593) tests for a mutation in the MITF gene. Esta prueba detecta dos variantes (alelos). El alelo M es dominante. Una o dos copias del alelo M resultan en el color de la capa de Macchiato. El alelo N es recesivo y no tiene efecto en el color básico.

The Coat Macchiato (Splashed White) test encloses the following results:

Result Macchiato

Coat Colour

Descripción

N/N

Non-Macchiato

 

Non-Macchiato. The basic colour is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/M

Macchiato

Macchiato pattern. One copy of the M allele. Horse has Macchiato coat pattern unless modified by other colour modifying genes. It can pass on either allele N or M to its offspring.

M/M

Macchiato

Macchiato pattern. Two copies of the M allele. Horse has Macchiato coat pattern unless modified by other colour modifying genes. It can only pass on allele M to its offspring.

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P512 Splashed White 1

Splashed white is a variable white spotting pattern characterized by a large blaze, extended white markings on legs, variable white spotting on belly, pink skin and often blue eyes. En otros casos, las áreas no pigmentadas son bastante pequeñas y no se pueden distinguir de los caballos con otros fenotipos de despigmentación más sutiles. Los caballos blancos salpicados a veces son sordos, sin embargo, la mayoría de los caballos blancos salpicados no son sordos. La pérdida de audición se debe a la muerte de las células ciliadas necesarias, causada por la ausencia de melanocitos en el oído interno. Aunque la mayoría de los caballos de salpicadura tienen pigmento alrededor del exterior de la oreja, el pigmento debe aparecer en el oído interno para evitar la pérdida de audición. Hay varias mutaciones diferentes identificadas que están asociadas con patrones blancos salpicados. The Coat White Spotting 1 test (P512) tests for the mutation known as SW1 in the MITF gene. Esta prueba detecta dos variantes (alelos). El alelo SW1 es dominante. Una o dos copias del alelo SW1 dan como resultado un blanco salpicado. El alelo N es recesivo y no tiene efecto en el color básico.

The Coat Colour White Spotting 1 test encloses the following results, in this scheme the results of the Coat Colour White Spotting 1 test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result White Spotting 1

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

Not Splashed White. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Not Splashed White The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Not Splashed White. The basic colour black is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/SW1

e/e + A/A, A/a or a/a

 

Chestnut/sorrel with Splashed White pattern

Splashed White pattern. One copy of the SW1 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or SW1 to its offspring.

N/SW1

E/E or E/e + A/A or A/a

Brown/bay with Splashed White pattern

Splashed White pattern. One copy of the SW1 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or SW1 to its offspring.

N/SW1

E/E or E/e + a/a

Black with Splashed White pattern

Splashed White pattern. One copy of the SW1 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or SW1 to its offspring.

SW1/SW1

e/e + A/A, A/a or a/a

Chestnut/sorrel with Splashed White pattern

Splashed White pattern. Two copies of the SW1 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele SW1 to its offspring.

SW1/SW1

E/E or E/e + A/A or A/a

Brown/bay with Splashed White pattern

Splashed White pattern. Two copies of the SW1 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele SW1 to its offspring.

SW1/SW1

E/E or E/e + a/a

Black with Splashed White pattern

Splashed White pattern. Two copies of the SW1 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele SW1 to its offspring.

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P513 Splashed White 2

Información sobre este test será publicada en breve.

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P514 Splashed White3

Splashed white is a variable white spotting pattern characterized by a large blaze, extended white markings on legs, variable white spotting on belly, pink skin and often blue eyes. En otros casos, las áreas no pigmentadas son bastante pequeñas y no se pueden distinguir de los caballos con otros fenotipos de despigmentación más sutiles. Los caballos blancos salpicados a veces son sordos, sin embargo, la mayoría de los caballos blancos salpicados no son sordos. La pérdida de audición se debe a la muerte de las células ciliadas necesarias, causada por la ausencia de melanocitos en el oído interno. Aunque la mayoría de los caballos de salpicadura tienen pigmento alrededor del exterior de la oreja, el pigmento debe aparecer en el oído interno para evitar la pérdida de audición. Hay varias mutaciones diferentes identificadas que están asociadas con patrones blancos salpicados. The Coat White Spotting 3 test (P514) tests for the mutation known as SW3 in the MITF gene. Esta prueba detecta dos variantes (alelos). El alelo SW3 es dominante. Una o dos copias del alelo SW3 dan como resultado un blanco salpicado. Se especula que dos copias del alelo SW3 son letales (el potro muere). El alelo N es recesivo y no tiene efecto en el color básico.

The Coat Colour White Spotting 3 test encloses the following results, in this scheme the results of the Coat Colour White Spotting 3 test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result White Spotting 3

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

Not Splashed White. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Not Splashed White The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Not Splashed White. The basic colour black is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/SW3

e/e + A/A, A/a or a/a

 

Chestnut/sorrel with Splashed White pattern

Splashed White pattern. One copy of the SW3 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or SW3 to its offspring.

N/SW3

E/E or E/e + A/A or A/a

Brown/bay with Splashed White pattern

Splashed White pattern. One copy of the SW3 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or SW3 to its offspring.

N/SW3

E/E or E/e + a/a

Black with Splashed White pattern

Splashed White pattern. One copy of the SW3 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can pass on either allele N or SW3 to its offspring.

SW3/SW3

e/e + A/A, A/a or a/a

Chestnut/sorrel with Splashed White pattern

Splashed White pattern. Two copies of the SW3 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele SW3 to its offspring.

SW3/SW3

E/E or E/e + A/A or A/a

Brown/bay with Splashed White pattern

Splashed White pattern. Two copies of the SW3 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele SW3 to its offspring.

SW3/SW3

E/E or E/e + a/a

Black with Splashed White pattern

Splashed White pattern. Two copies of the SW3 allele. The horse will display some degree of white spotting but the specific pattern cannot be predicted, unless modified by other colour modifying genes. It can only pass on allele SW3 to its offspring.

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P659 Coat Colour Roan

Roan is a white patterning coat colour trait of intermixed white and coloured hairs in the body while the head, lower legs, mane and tail remain colored. Los caballos Ruano nacen con el patrón, aunque puede que no sea obvio hasta que se desprenda el pelaje. Los pelos blancos y de colores se mezclan de manera uniforme en caballos que heredan el gen Ruano clásico, que puede diferenciarlo de varios patrones mímicos llamados roaning. Los patrones ruanos tienden a ser desiguales en la distribución de los pelos blancos y no se ha definido la herencia de la ondulación. La mutación que causa el color de capa Ruano aún no ha sido identificada. La prueba de capa Ruano (P659) analiza los marcadores de ADN que se asocian con el color de la capa Ruano en varias razas. Los marcadores de ADN se pueden utilizar para determinar si un caballo tiene la mutación Ruano y cuántas copias. Esta prueba detecta tres variantes (alelos), Rn, Rn * y N. Es dominante el alelo Rn. Una o dos copias del alelo Rn resultan en un color de capa Ruano. El alelo Rn * es muy infrecuente y no siempre asociado con el color de la capa Ruano, este alelo sólo se ha observado en caballos andadores de Tennessee y caballos de las montañas rocosas. El alelo N es recesivo y no tiene efecto en el color básico.

The Coat Colour Roan test encloses the following results, in this scheme the results of the Coat Colour Roan test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Roan

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

Not Roan. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Not Roan. The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Not Roan. The basic colour black is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

Rn/N

e/e + A/A, A/a or a/a

 

Chestnut/sorrel Roan

One copy of the dominant Rn allele. The colour is chestnut/sorrel roan, unless modified by other colour modifying genes. It can pass on either allele N or Rn to its offspring.

Rn/N

E/E or E/e + A/A or A/a

Brown/bay Roan

One copy of the dominant Rn allele. The colour is brown/bay roan, unless modified by other colour modifying genes. It can pass on either allele N or Rn to its offspring.

Rn/N

E/E or E/e + a/a

Black Roan

One copy of the dominant Rn allele. The colour is black roan, unless modified by other colour modifying genes. It can pass on either allele N or Rn to its offspring.

Rn*/N

e/e + A/A, A/a or a/a

Chestnut/sorrel or Chestnut/sorrel Roan

One copy of the uncommon Rn* allele. The colour can be chestnut/sorrel or chestnut/sorrel roan, unless modified by other colour modifying genes. It can pass on either allele N or Rn* to its offspring.

Rn*/N

E/E or E/e + A/A or A/a

Brown/bay or Brown/bay Roan

One copy of the uncommon Rn* allele. The colour can be brown/bay or brown/bay roan, unless modified by other colour modifying genes. It can pass on either allele N or Rn* to its offspring.

Rn*/N

E/E or E/e + a/a

Black or Black Roan

One copy of the uncommon Rn* allele. The colour can be black or black roan, unless modified by other colour modifying genes. It can pass on either allele N or Rn* to its offspring.

Rn/Rn

e/e + A/A, A/a or a/a

Chestnut/sorrel Roan

Two copies of the dominant Rn allele. The colour is chestnut/sorrel roan, unless modified by other colour modifying genes. It can only pass on allele Rn to its offspring.

Rn/Rn

E/E or E/e + A/A or A/a

Brown/bay Roan

Two copies of the dominant Rn allele. The colour is brown/bay roan, unless modified by other colour modifying genes. It can only pass on allele Rn to its offspring.

Rn/Rn

E/E or E/e + a/a

Black Roan

Two copies of the dominant Rn allele. The colour is black roan, unless modified by other colour modifying genes. It can only pass on allele Rn to its offspring.

Rn/Rn*

e/e + A/A, A/a or a/a

Chestnut/sorrel Roan

One copy of the dominant Rn allele and one copy of the uncommon Rn* allele. The colour is chestnut/sorrel roan, unless modified by other colour modifying genes. It can pass on either allele Rn or Rn* to its offspring.

Rn/Rn*

E/E or E/e + A/A or A/a

Brown/bay Roan

One copy of the dominant Rn allele and one copy of the uncommon Rn* allele. The colour is brown/bay roan, unless modified by other colour modifying genes. It can pass on either allele Rn or Rn* to its offspring.

Rn/Rn*

E/E or E/e + a/a

Black Roan

One copy of the dominant Rn allele and one copy of the uncommon Rn* allele. The colour is black roan, unless modified by other colour modifying genes. It can pass on either allele Rn or Rn* to its offspring.

Rn*/Rn*

e/e + A/A, A/a or a/a

Chestnut/sorrel or Chestnut/sorrel Roan

Two copies of the uncommon Rn* allele. The colour can be chestnut/sorrel or chestnut/sorrel roan, unless modified by other colour modifying genes. It can only pass on allele Rn* to its offspring.

Rn*/Rn*

E/E or E/e + A/A or A/a

Brown/bay or Brown/bay Roan

Two copies of the uncommon Rn* allele. The colour can be brown/bay or brown/bay roan, unless modified by other colour modifying genes. It can only pass on allele Rn* to its offspring.

Rn*/Rn*

E/E or E/e + a/a

Black or Black Roan

Two copies of the uncommon Rn* allele. The colour can be black or black roan, unless modified by other colour modifying genes. It can only pass on allele Rn* to its offspring.

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P785 Coat Colour Sabino 1

Sabino is a general description for a group of similar white spotting patterns. El patrón sabino se describe como manchas irregulares, por lo general en las piernas, el vientre y la cara, a menudo con un marcado alrededor de los bordes de las marcas blancas. Se ha descubierto una mutación que produce un tipo de patrón sabino, se le ha llamado Sabino1 porque no está presente en todos los caballos con patrón sabino. Probablemente existirán más mutaciones que influyan en otros patrones sabinos. La prueba Color de Capa Sabino 1 (P785) analiza el estado genético del gen KIT. Este gen tiene dos variantes (alelos). El alelo SB1 es semi- dominante. Una copia del alelo SB1 da como resultado caballos con marcas Sabino rotas y posiblemente solo una pequeña cantidad de blanco. Dos copias del alelo SB1 dan como resultado al menos un 90% de blanco, también conocido como Sabino-blanco. El alelo N es recesivo y no tiene efecto en el color básico.

The Coat Colour Sabino 1 test encloses the following results, in this scheme the results of the Coat Colour Sabino 1 test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Sabino 1

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

Not Sabino 1. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Not Sabino 1. The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Not Sabino 1. The basic colour is not black modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/SB1

e/e + A/A, A/a or a/a

 

Chestnut/sorrel sabino

Sabino 1 pattern. One copy of the SB1 allele. Horse typically may have 2 or more white legs, blaze, spots or roaning in the midsection and jagged margins around white areas unless modified by other colour modifying genes. It can pass on either allele N or SB1 to its offspring.

N/SB1

E/E or E/e + A/A or A/a

Brown/bay sabino

Sabino 1 pattern. One copy of the SB1 allele. Horse typically may have 2 or more white legs, blaze, spots or roaning in the midsection and jagged margins around white areas unless modified by other colour modifying genes. It can pass on either allele N or SB1 to its offspring.

N/SB1

E/E or E/e + a/a

Black sabino

Sabino 1 pattern. One copy of the SB1 allele. Horse typically may have 2 or more white legs, blaze, spots or roaning in the midsection and jagged margins around white areas unless modified by other colour modifying genes. It can pass on either allele N or SB1 to its offspring.

SB1/SB1

e/e + A/A, A/a or a/a

 

Chestnut/sorrel sabino

Sabino 1 pattern. Two copies of the SB1 allele. Horse is complete or nearly complete white unless modified by other colour modifying genes. It can only pass on allele SB1 to its offspring.

SB1/SB1

E/E or E/e + A/A or A/a

Brown/bay sabino

Sabino 1 pattern. Two copies of the SB1 allele. Horse is complete or nearly complete white unless modified by other colour modifying genes. It can only pass on allele SB1 to its offspring.

SB1/SB1

E/E or E/e + a/a

Black sabino

Sabino 1 pattern. Two copies of the SB1 allele. Horse is complete or nearly complete white unless modified by other colour modifying genes. It can only pass on allele SB1 to its offspring.

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P807 Coat Colour Grey

A horse that inherits a Grey coat colour can be born in any colour. The grey gene causes progressive depigmentation (fading) of the hair and is considered to be the “strongest” of all coat colour modifying genes. El proceso de despigmentación puede durar años, pero una vez que se despigmenta el cabello, el color original nunca regresará. Algunos caballos grises se vuelven completamente blancos, mientras que otros mantendrán pequeñas manchas sin decoloración (también llamadas pulgas). A horse can also carry mutations for other modifying genes which can further affect its coat colour.

The Coat Colour Grey test (P807) tests for the genetic status of the STX17 gene. Este gen tiene dos variantes (alelos). El alelo dominante G da como resultado el color de la capa gris y el alelo recesivo N no tiene un efecto sobre el color básico. El alelo dominante G tiene una duplicación de una parte del ADN. The test does not discriminate between horses carrying 1 or 2 copies of  the duplication (N/G or G/G). Todos los caballos que lleven la duplicación se volverán grises.

The Coat Colour Grey test encloses the following results, in this scheme the results of the Coat Colour Grey test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Grey

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

Horse will not turn grey. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Horse will not turn grey. The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Horse will not turn grey. The basic colour black is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/G or G/G

e/e + A/A, A/a or a/a

 

Grey (born chestnut/sorrel)

Horse is born with basic colour chestnut/sorrel (unless modified by other colour modifying genes) and will turn grey. One copy or two copies of the G allele. It can pass on either allele N or G to its offspring.

N/G or G/G

E/E or E/e + A/A or A/a

Grey (born bay/brown)

Horse is born with basic colour bay/brown (unless modified by other colour modifying genes) and will turn grey. One copy or two copies of the G allele. It can pass on either allele N or G to its offspring.

N/G or G/G

E/E or E/e + a/a

Grey (born black)

Horse is born with basic colour black (unless modified by other colour modifying genes) and will turn grey. One copy or two copies of the G allele. It can pass on either allele N or G to its offspring.

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P902 Coat Colour Overo-factor (OLWS)

The Overo coat pattern is a white spotting pattern with white patches on the side with a “frame” of colour surrounding the white. A horse can also carry mutations for other modifying genes which can further affect its coat colour. Si bien los caballos de color Overo son deseables, la mutación que causa el color overo está vinculada a una condición fatal conocida como Síndrome de Overo Lethal White o OLWS. Un potro con OLWS nace todo blanco y muere por complicaciones de anomalías del tracto intestinal. La prueba Color de Capa Overo (P902) analiza un factor genético que afecta la función del gen EDNRB. Este gen tiene dos variantes (alelos). El alelo O es semi-dominante. Una copia del alelo O da como resultado caballos con patrón de capa overo. Dos copias del alelo O resultan en un potro blanco letal (OLWS). El alelo N es recesivo y no tiene efecto en el color básico.

The Coat Colour Overo-factor test encloses the following results, in this scheme the results of the Coat Colour Overo-factor test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Overo-factor

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

Not Overo. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Not Overo. The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Not Overo. The basic colour black is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/O

e/e + A/A, A/a or a/a

 

Chestnut/sorrel overo

Overo pattern. One copy of the O allele. The horse has the desirable frame overo pattern unless modified by other colour modifying genes. It can pass on either allele N or O to its offspring.

N/O

E/E or E/e + A/A or A/a

Brown/bay overo

Overo pattern. One copy of the O allele. The horse has the desirable frame overo pattern unless modified by other colour modifying genes. It can pass on either allele N or O to its offspring.

N/O

E/E or E/e + a/a

Black overo

Overo pattern. One copy of the O allele. The horse has the desirable frame overo pattern unless modified by other colour modifying genes. It can pass on either allele N or O to its offspring.

O/O

Any result

Lethal (OLWS)

Foal with Overo Lethal White Syndrome (OLWS), lethal.

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P903 Coat Colour Tobiano

The Tobiano coat pattern usually involves white on all four legs below the hocks and knees and rounded white spots on the body with sharp, clean edges. La cabeza es oscura, con marcas blancas como las de un caballo de color sólido. El blanco en el cuerpo generalmente cruzará la línea superior del caballo. La piel subyacente a las manchas blancas es rosada y debajo de las áreas coloreadas es negra. Los ojos suelen ser marrones, pero uno o ambos pueden ser azules o parcialmente azules. The tail can be two colors, a characteristic seldom seen in horses that are not tobiano. A horse can also carry mutations for other modifying genes which can further affect its coat colour.

The Coat Colour Tobiano test (P903) tests for a genetic factor that affects the function of the KIT gene. Este gen tiene dos variantes (alelos). El alelo dominante TO da como resultado el patrón de Tobiano y el alelo recesivo N no tiene un efecto sobre el color básico.

The Coat Colour Tobiano test encloses the following results, in this scheme the results of the Coat Colour Tobiano test are shown in combination with the possible results for the tests that determine the basic Coat Colour (Coat Colour Chestnut and Coat Colour Agouti test):

Result Tobiano

Result Chestnut + Agouti

Coat Colour

Descripción

N/N

e/e + A/A, A/a or a/a

 

Chestnut, Sorrel

 

Not Tobiano. The basic colour chestnut/sorrel is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + A/A or A/a

Bay, Brown

Not Tobiano. The basic colour bay/brown is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

E/E or E/e + a/a

Black

Not Tobiano. The basic colour black is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/TO

e/e + A/A, A/a or a/a

 

Chestnut/sorrel tobiano

One copy of the dominant TO allele. The colour is chestnut/sorrel tobiano unless modified by other colour modifying genes. It can pass on either allele N or TO to its offspring.

N/TO

E/E or E/e + A/A or A/a

Bay/brown tobiano

One copy of the dominant TO allele. The colour is bay/brown tobiano unless modified by other colour modifying genes. It can pass on either allele N or TO to its offspring.

N/TO

E/E or E/e + a/a

Black tobiano

One copy of the dominant TO allele. The colour is black tobiano unless modified by other colour modifying genes. It can pass on either allele N or TO to its offspring.

TO/TO

e/e + A/A, A/a or a/a

 

Chestnut/sorrel tobiano

Two copies of the dominant TO allele. The colour is chestnut/sorrel tobiano unless modified by other colour modifying genes. It can only pass on allele TO to its offspring.

TO/TO

E/E or E/e + A/A or A/a

Bay/brown tobiano

Two copies of the dominant TO allele. The colour is bay/brown tobiano unless modified by other colour modifying genes. It can only pass on allele TO to its offspring.

TO/TO

E/E or E/e + a/a

Black tobiano

Two copies of the dominant TO allele. The colour is black tobiano unless modified by other colour modifying genes. It can only pass on allele TO to its offspring.

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P305 Coat Colour Appaloosa Pattern-1 (PATN1)

The Appaloosa spotting pattern, also known as Leopard Complex spotting (LP) includes a highly variable group of white spotting- or depigmentation patterns in horses. Los caballos Appaloosa tienen tres características identificables adicionales: piel moteada alrededor del hocico, ano y genitales, cascos a rayas y esclera blanca alrededor de los ojos. LP es el resultado de una mutación incompleta dominante en el gen TRPM1, también conocido como el gen LP. El gen LP permite la expresión de varios patrones de moteado de de leopardo, mientras que otros genes determinan la extensión (o cantidad) del blanco. Uno de los genes que se asocia con una mayor cantidad de blanco en caballos LP ha sido identificado (RFWD3) y se ha denominado Patrón-1 (PATN1) para el primer gen patrón. La prueba Color Appaloosa Pattern-1 (PATN1) (P305) analiza el estado del gen PATN1. Este gen tiene dos variantes (alelos). El alelo dominante PATN1 da como resultado una mayor cantidad de blanco en caballos que llevan al menos una copia del alelo LP en el gen LP. El alelo recesivo N no tiene un efecto sobre el color básico. Los caballos que tienen una copia del alelo LP, en combinación con al menos una copia del alelo PATN1, generalmente tienen un patrón Leopard o Leopardo cercano. Los caballos que tienen dos copias del alelo LP en combinación con al menos una copia del alelo PATN1 con mayor frecuencia tienen un patrón de pocos puntos o cerca de pocos puntos. Horses that have at least one copy of the  PATN1 allele but do not have a copy of the LP allele will not have a Appaloosa spotting pattern but can pass on the PATN1 allele to their offspring.

The Coat Colour Appaloosa Pattern-1 (PATN1) test encloses the following results, in this scheme the results of the Coat Colour Appaloosa Pattern-1 (PATN1) test are shown in combination with the possible results for the LP Gene.

Result PATN1

Result LP

Coat Colour

Descripción

N/N

N/N

No Appaloosa

The basic colour is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/N

N/LP

Blanket appaloosa

It can only pass on allele N to its offspring.

N/N

LP/LP

Snow cap appaloosa

It can only pass on allele N to its offspring. The horse suffers from Congenital Stationary Night Blindness (CSNB).

N/PATN1

N/N

No Appaloosa

The basic colour is not modified unless modified by other colour modifying genes. It can pass on either allele N or PATN1 to its offspring.

N/PATN1

N/LP

Leopard or a near Leopard pattern

It can pass on either allele N or PATN1 to its offspring.

N/PATN1

LP/LP

Few-spot or near Few spot pattern.

It can pass on either allele N or PATN1 to its offspring. The horse suffers from Congenital Stationary Night Blindness (CSNB).

PATN1/PATN1

N/N

No Appaloosa

The basic colour is not modified unless modified by other colour modifying genes. It can only pass on allele PATN1 to its offspring.

PATN1/PATN1

N/LP

Leopard or a near Leopard pattern

It can only pass on allele PATN1 to its offspring.

PATN1/PATN1

LP/LP

Few-spot or near Few spot pattern

It can only pass on allele PATN1 to its offspring. The horse suffers from Congenital Stationary Night Blindness (CSNB).

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P311 CSNB / Leopard Spotting

The Appaloosa spotting pattern, also known as Leopard Complex spotting (LP) includes a highly variable group of white spotting- or depigmentation patterns in horses. Los caballos Appaloosa tienen tres características identificables adicionales: piel moteada alrededor del hocico, ano y genitales, cascos a rayas y esclera blanca alrededor de los ojos. El patrón de Appaloosa es el resultado de una mutación dominante incompleta en el gen TRPM1, también conocido como el gen LP. El gen LP permite la expresión de varios patrones de moteado de de leopardo, mientras que otros genes determinan la extensión (o cantidad) del blanco. La prueba CSNB / Punteado de Leopardo (P311) analiza el estado del gen LP (TRPM1). Este gen tiene dos variantes (alelos). El alelo LP es incompleto-dominante y la expresión del patrón de Appaloosa es variable, desde patrones ausentes hasta extremadamente blancos. Al menos una copia del alelo LP permite la expresión del patrón de Appaloosa. La cantidad de blanco presente no está relacionada con la cantidad de los genes, los caballos con dos copias del alelo LP pueden tener una expresión mínima del patrón blanco. El alelo recesivo N no tiene un efecto sobre el color básico. La variabilidad en la cantidad de blanco en caballos de color Appaloosa está controlada por otros genes, uno de los cuales es PATN1. Los caballos que tienen una copia del alelo LP, en combinación con al menos una copia del alelo PATN1, generalmente tienen un patrón Leopard o Leopardo cercano. Los caballos que tienen dos copias del alelo LP en combinación con al menos una copia del alelo PATN1 con mayor frecuencia tienen un patrón de pocos puntos o cerca de pocos puntos. Los caballos que tienen dos copias del alelo LP sufren de ceguera nocturna estacionaria congénita (CSNB), que es la incapacidad de ver en condiciones de poca luz o sin luz.

The CSNB / Leopard Spotting test encloses the following results, in this scheme the results of the CSNB / Leopard Spotting test are shown in combination with the possible results for the Coat Colour Appaloosa Pattern-1 (PATN1) test.

Result LP

Result PATN1

Coat Colour

Descripción

N/N

N/N

No Appaloosa

The basic colour is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/LP

N/N

Blanket appaloosa

It can pass on either allele N or LP to its offspring.

LP/LP

N/N

Snow cap appaloosa

It can only pass on allele LP to its offspring. The horse suffers from Congenital Stationary Night Blindness (CSNB)

N/N

N/PATN1

No Appaloosa

The basic colour is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring..

N/LP

N/PATN1

Leopard or a near Leopard pattern

It can pass on either allele N or LP to its offspring.

LP/LP

N/PATN1

Few-spot or near Few spot pattern.

It can only pass on allele LP to its offspring. The horse suffers from Congenital Stationary Night Blindness (CSNB)

N/N

PATN1/PATN1

No Appaloosa

The basic colour is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring.

N/LP

PATN1/PATN1

Leopard or a near Leopard pattern

It can pass on either allele N or LP to its offspring.

LP/LP

PATN1/PATN1

Few-spot or near Few spot pattern

It can only pass on allele LP to its offspring. The horse suffers from Congenital Stationary Night Blindness (CSNB)

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Date: 31 January 2019, version 6