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K427

The coat pattern known as “Ticking” is one of the variations on a tabby coat in cats, where the typical stripes are blended into a more sandy, even colour.

10 días laborables

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Especificaciones

Breeds

,

Gene

Organ

specimen

Hisopo, sangre EDTA, sangre Heparina, Semen, Tejido

Mode of Inheritance

Chromosome

Also known as

Year Published

Información específica de la prueba

The coat pattern known as “Ticking” is one of the variations on a tabby coat in cats, where the typical stripes are blended into a more sandy, even colour. A ticked coat can be present due to one of the two known dominant mutations in the Dickkopf WNT Signaling Pathway Inhibitor 4 (DKK4) gene, which regulates hair follicle development and pigmentation. Both mutations lead to the distinctive characteristics of the coat.

The mutation tested for here is known as Ti^A and is found in the Abyssinian and Somali breeds. A second mutation (Ti^CK) seem to be present in more breeds: Abyssinian, Somali, Burmese, Maine Coon, Siamese, Exotic Longhair and Oriental Short- and longhair breeds.

Características clínicas

Ticked describes a coat pattern in which a single hair banding occurs without the coat itself being patterned. Meaning that ticked cats have a more evenly-blended coat pattern than other tabby cats, with a colour distribution often described as “sand-like” or “salt-and-pepper”. In some cases, faint striping (ghost stripes) may still be visible on the lower legs, face and tail. As with all forms of tabby, a ticked coat is only possible if the cat is not affected by the non-agouti mutation (not a/a) and the tabby locus can only be expressed in cats which don’t have mutations on the ticked locus.

Información adicional

El color del pelaje es un rasgo intrincado que implica una combinación de múltiples genes diferentes. Analizando una variedad de loci diferentes darán la predicción más completa de la genética del color del pelaje de un gato.

Referencias

Pubmed ID: 33780570

Omia ID: 1484-9685

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