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Coat colour in dogs is controlled by a wide range of different genes working together.
10 días laborables
Only available in bundles
Especificaciones
| Breeds | |
|---|---|
| Gene | |
| Chromosome | 5 |
| Mutation | c.233G>T |
| Mode of Inheritance | Autosómico dominante |
| Organ | |
| Specimen | Hisopo, sangre EDTA, sangre Heparina, Semen, Tejido |
| Also known as | E^G |
Información específica de la prueba
Coat colour in dogs is controlled by a wide range of different genes working together. These genes are often referred to as ‘loci’. The Extension, or E-Locus, corresponds to the gene ‘melanocortin 1 receptor’ (MC1R), which is involved in the regulation of pigment production.
This E-locus variant, designated as Grizzle or Eg, is a dominant mutation unique to the Saluki and Afghan Hound. It results in a coat colouration pattern known as ‘grizzle’ in the Saluki, and as ‘domino’ in the Afghan Hound.
Características clínicas
Affected dogs develop darkened fur on the top and sides of the body and the outside of the limbs. The contrast between the darker hair on the head with the lighter hair on the face in a distinct V-shaped hairline pattern is often called a ‘widow’s peak’.
Información adicional
El color del pelaje es un rasgo intrincado que implica una combinación de múltiples genes diferentes. Las pruebas para una variedad de loci diferentes darán la predicción más completa de la genética del color del pelaje de un perro.
Referencias
Pubmed ID: 20525767
Year published: 2010
Omia ID: 1495
Omia variant ID: 32