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Polydactyly, also known as Preaxial Polydactyly (PPD) is a developmental abnormality in dogs that causes the growth of extra toes on the hind legs.
10 días laborables
Especificaciones
| Breeds | Belgian Malinois, Biewer Terrier, Huntaway, New Zealand Heading Dog, Perro Pastor Shetland (Sheltie), Schnauzer stándard, Norwegian Lundehund, Poodle (Standard), Beagle, Cocker Spaniel, Rottweiler, Shih-Tzu, Yorkshire Terrier |
|---|---|
| Gene | |
| Chromosome | 16 |
| Mode of Inheritance | Autosómico dominante |
| Organ | |
| Specimen | Hisopo, sangre EDTA, sangre Heparina, Semen, Tejido |
Información específica de la prueba
Polydactyly, also known as Preaxial Polydactyly (PPD) is a developmental abnormality in dogs that causes the growth of extra toes on the hind legs. Specifically, polydactyly restores the first toe that was lost over the course of the evolution of the wolf, giving affected dogs a fifth toe known as a “dewclaw”. This specific variant (DC-2) is caused by a dominant mutation to the Limb Development Membrane Protein 1 (LMBR1) gene that affects the expression of the sonic hedgehog (SHH) gene.
This test measures the mutation known as DC-2. Another mutation, DC-1, is found in Sapsari and Tosa dogs.
Características clínicas
Los perros afectados desarrollan un dedo extra, o espolón, en sus patas traseras.
Información adicional
Referencias
Pubmed ID: 18689889
Year published: 2008
Omia ID: 810
Omia variant ID: