The Appaloosa spotting pattern, also known as Leopard Complex spotting (LP) includes a highly variable group of white spotting- or depigmentation patterns in horses. Los caballos Appaloosa tienen tres características identificables adicionales: piel moteada alrededor del hocico, ano y genitales, cascos a rayas y esclera blanca alrededor de los ojos. LP es el resultado de una mutación incompleta dominante en el gen TRPM1, también conocido como el gen LP. El gen LP permite la expresión de varios patrones de moteado de de leopardo, mientras que otros genes determinan la extensión (o cantidad) del blanco. Uno de los genes que se asocia con una mayor cantidad de blanco en caballos LP ha sido identificado (RFWD3) y se ha denominado Patrón-1 (PATN1) para el primer gen patrón. La prueba Color Appaloosa Pattern-1 (PATN1) (P305) analiza el estado del gen PATN1. Este gen tiene dos variantes (alelos). El alelo dominante PATN1 da como resultado una mayor cantidad de blanco en caballos que llevan al menos una copia del alelo LP en el gen LP. El alelo recesivo N no tiene un efecto sobre el color básico. Los caballos que tienen una copia del alelo LP, en combinación con al menos una copia del alelo PATN1, generalmente tienen un patrón Leopard o Leopardo cercano. Los caballos que tienen dos copias del alelo LP en combinación con al menos una copia del alelo PATN1 con mayor frecuencia tienen un patrón de pocos puntos o cerca de pocos puntos. Horses that have at least one copy of the PATN1 allele but do not have a copy of the LP allele will not have a Appaloosa spotting pattern but can pass on the PATN1 allele to their offspring.
The Coat Colour Appaloosa Pattern-1 (PATN1) test encloses the following results, in this scheme the results of the Coat Colour Appaloosa Pattern-1 (PATN1) test are shown in combination with the possible results for the LP Gene.
|
Result PATN1 |
Result LP |
Coat Colour |
Descripción |
|---|---|---|---|
|
N/N |
N/N |
No Appaloosa |
The basic colour is not modified unless modified by other colour modifying genes. It can only pass on allele N to its offspring. |
|
N/N |
N/LP |
Blanket appaloosa |
It can only pass on allele N to its offspring. |
|
N/N |
LP/LP |
Snow cap appaloosa |
It can only pass on allele N to its offspring. The horse suffers from Congenital Stationary Night Blindness (CSNB). |
|
N/PATN1 |
N/N |
No Appaloosa |
The basic colour is not modified unless modified by other colour modifying genes. It can pass on either allele N or PATN1 to its offspring. |
|
N/PATN1 |
N/LP |
Leopard or a near Leopard pattern |
It can pass on either allele N or PATN1 to its offspring. |
|
N/PATN1 |
LP/LP |
Few-spot or near Few spot pattern. |
It can pass on either allele N or PATN1 to its offspring. The horse suffers from Congenital Stationary Night Blindness (CSNB). |
|
PATN1/PATN1 |
N/N |
No Appaloosa |
The basic colour is not modified unless modified by other colour modifying genes. It can only pass on allele PATN1 to its offspring. |
|
PATN1/PATN1 |
N/LP |
Leopard or a near Leopard pattern |
It can only pass on allele PATN1 to its offspring. |
|
PATN1/PATN1 |
LP/LP |
Few-spot or near Few spot pattern |
It can only pass on allele PATN1 to its offspring. The horse suffers from Congenital Stationary Night Blindness (CSNB). |